Sweating was temporary in all cases and was mild for doses of 3.0 mg or less but was extensive (beads of sweat over the entire body and dripping) for the 10 mg dose. Perform FTAI 0 to 24 hours after the second dose of FACTREL Injection, or inseminate cows on detected estrus using standard herd practices. Clinically, a slight transitory increase in heart rate was detected. Hormonal injection in prepubertal gilts and sows with a combination of eCG and hCG induces rapid follicle growth and estrus in 4 to 5 days. Hormonal injection in prepubertal gilts and sows with a combination also induces rapid follicle growth and estrus in 4 to 5 days. Swine: The most frequently observed side effects were erythema and pruritus, slight incoordination, nesting behavior, itching, urination, defecation, abdominal muscle spasms, tail movements, hyperpnea or dyspnea, increased vocalization, salivation, and at the 100 mg (10x) dose only, possible vomiting. A prescription is required to purchase this product. Women of childbearing age, asthmatics, and persons with bronchial and other respiratory problems should exercise extreme caution when handling this product. Meat Withholding: None in cattle. These side effects are transitory, lasting from 10 minutes to 3 hours, and were not detrimental to the health of the animal. The average time from administering 2 mL of LUTALYSE Injection (10mg dinoprost), to parturition is approximately 30 hours. 5 mg dinoprost/mL as dinoprost tromethamine. After 14 days, recovery rate of treated cattle was no different than that of non-treated cattle. Thus, the 100 mg dose gave a safety margin of 10 to 20X for a single injection or 80 to 160X for the 8 daily injections. The statistical predicted relative abortion rate based on the dose titration data, was about 93% for the 5 mL (25 mg) LUTALYSE Injection dose for cattle injected up to 100 days of gestation. CONTACT INFORMATION The dose for all indicated uses in cattle is 5 ml Lutalyse (25 mg dinoprost) Mares. For Unobserved (Silent) Estrus in Lactating Dairy Cows with a Corpus Luteum. Estrus may be induced in diestrous mares (having a corpus luteum that is 5 or more days postovulation) by treatment with natural PGF 2 (10 mg, IM) or cloprostenol (250 mcg, IM) to lyse the corpus luteum. Look for signs of labor to start at 20 to 26 hours after the induction injection. Select one or more newsletters to continue. Using bulls to breed large numbers of cattle in heat following LUTALYSE Injection will require proper management of bulls and cattle. Changes were detected in all treated groups for clinical (reduced sensitivity to pain; locomotor incoordination; hypergastromotility; sweating; hyperthermia; labored respiration), blood chemistry (elevated cholesterol, total bilirubin, LDH, and glucose), and hematology (decreased eosinophils; increased hemoglobin, hematocrit, and erythrocytes) measurements. Each mL contains dinoprost tromethamine equivalent to 5 mg dinoprost: also, benzyl alcohol, 16.5 mg added as preservative and water for injection. Inject a dose of 5 mL LUTALYSE Injection (25mg dinoprost) intramuscularly either once or twice at a 10 to 12 day interval. Rectal temperature was decreased during the interval 0.5 until 1.0, 3 to 4, or 5 hours after injection for 0.25 and 1.0 mg, 2.5 and 3.0, or 5.0 and 10.0 mg dose groups, respectively. For Unobserved (Silent) Estrus in Lactating Dairy Cows with a Corpus Luteum. Administer LUTALYSE (25 mg dinoprost, as dinoprost tromethamine) Injection by intramuscular injection 6-8 days after the first dose of FACTREL Injection. We comply with the HONcode standard for trustworthy health information. We leave you the link to expand this information and know how to make a correct exposure to the male or how heat is detected in the sow. Approved by FDA under NADA # 108-901 When necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid. Each mL contains dinoprost tromethamine equivalent to 5 mg dinoprost: also, benzyl alcohol, 16.5mg added as preservative and water for injection. 7. Lutalyse won't bring an anestrus cow into heat, it will only induce it in cows that are already cycling. Inject 5 mL LUTALYSE Injection (equivalent to 5 mg/mL dinoprost) 1 day prior to EAZI-BREED CIDR Cattle Insert removal, on Day 6 of the 7 day administration period. How do you tell if a cow is in heat? Management Considerations: Several factors must be considered for the successful use of LUTALYSE Injection for parturition induction in swine. The key reproductive event that determines when females begin their reproductive cycles is the onset of estrus. Rectal temperature was decreased during the interval 0.5 until 1.0, 3 to 4, or 5 hours after injection for 0.25 and 1.0 mg, 2.5 and 3.0, or 5.0 and 10.0 mg dose groups, respectively. Dexamethasone: 30 mg (at least 6 mL IM injection) Abortion will usually happen within 5 days of treatment. Prostaglandins, especially PGEs and PGFs, have been shown, in certain species, to 1)increase at time of parturition in amniotic fluid, maternal placenta, myometrium, and blood, 2)stimulate myometrial activity, and 3)to induce either abortion or parturition. Based on the dates you gave, you were trying to get her to breed back at 30-40 days which is tough even with a CIDR but Lutalyse is useless for that. LUTALYSE Injection is indicated for parturition induction in swine when injected within 3days of normal predicted farrowing. Usage Lutalyse is used to control estrus time in estrous-cycling mares. No vial stopper should be entered more than 20 times. A 14-day continuous intravenous infusion study in rats at 20 mg PGF2 per kg body weight indicated prostaglandins of the F series could induce bone deposition. one of the most widely use d natural polysaccharides in the food, agriculture, textile, pol-. In pigs, evaluation was made of clinical observations, food consumption, clinical pathologic determinations, body weight changes, urinalysis, organ weights, and gross and microscopic observations following treatment with single doses of 10, 30, 50 and 100 mg dinoprost administered intramuscularly. Lutalyse for goats can be effective in changing phase length and well as addressing "cystic" does and has been shown to help some does "reset" hormonally and resolve some fertility issues. Cattle expressing estrus following LUTALYSE Injection are receptive to breeding by a bull. For estrus synchronization in beef cows, beef heifers and replacement dairy heifers, For unobserved (silent) estrus in lactating dairy cows with a corpus luteum, For treatment of pyometra (chronic endometritis) in cattle, For abortion in beef cows, beef heifers and replacement dairy heifers, For use with FACTREL (gonadorelin injection) Injection to synchronize estrous cycles to allow fixed-time artificial insemination (FTAI) in lactating dairy cows, For use with EAZI-BREED CIDR (progesterone intravaginal insert) Cattle Insert for synchronization of estrus in lactating dairy cows, For use with EAZI-BREED CIDR (progesterone intravaginal insert) Cattle Insert for synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, advancement of first postpartum estrus in suckled beef cows, and advancement of first pubertal estrus in beef heifers, For controlling the timing of estrus in estrous cycling mares, For difficult-to-breed mares (clinically anestrous mares that have a corpus luteum). The estrus response is high within 48-96 hours. The half-life of dinoprost in bovine blood has been reported to be on the order of minutes. No apparent differences were observed between the intramuscular and subcutaneous routes of administration. THIS SERVICE AND DATA ARE PROVIDED "AS IS". One anaphylactic reaction of several hundred mares treated with LUTALYSE Injection was reported but was not confirmed. 2. Day 14 3cc lutalyse. Return to normal was defined as evacuation of fluid and return of the uterine horn size to 40mm or less based on palpation per rectum at 14 and 28 days. Mares did not appear to sustain adverse effects following termination of the side effects. However, induction of parturition or abortion with any exogenous compound may precipitate dystocia, fetal death, retained placenta and/or metritis, especially at latter stages of gestation. 3. For Treatment of Pyometra (chronic endometritis) in Cattle. Mare pregnancy status should be determined prior to treatment since LUTALYSE Injection has been reported to induce abortion and parturition when sufficient doses were administered. Treatment of such mares with LUTALYSE Injection usually results in regression of the corpus luteum followed by estrus and/or ovulation. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. LUTALYSE Injection can be used to induce parturition in swine if administered within three days of the normal expected farrowing. Ltd. Dinoprost tromethamine is a white or slightly off-white crystalline powder that is readily soluble in water at room temperature in concentrations to at least 200 mg/mL. A slight and marked embryo lethal effect was observed in dams given 1.0 and 5.0 mg dinoprost/kg/ day respectively. Cattle: Limited salivation has been reported in some instances. Cattle serum collected during 24 hours after doses of 0 to 250 mg dinoprost have been assayed by RIA for dinoprost and the 15-keto metabolites. after injection. The response to treatment varies by individual animals with a mean interval from administration of 2 mL LUTALYSE Injection (10 mg dinoprost) to parturition of approximately 30 hours. These cookies will be stored in your browser only with your consent. 2. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Induction is a procedure used to advance estrus. You can induce labor with as little as 1/2 cc of Lutalyse, but most people use 2 ccs IM (which is what we use). LUTALYSE Injection is available in 30 and 100 mL vials. LUTALYSE Injection (5 mg dinoprost/mL) is a sterile solution containing the naturally occurring prostaglandin F2 alpha (dinoprost) as the tromethamine salt. Swine AI, Pregnancy, & Parturition Flashcards | Quizlet Lutalyse POM - from 45.79 | Hyperdrug Using bulls to breed large numbers of cattle in heat following LUTALYSE will require proper management of bulls and cattle. As with any multi-dose vial, practice aseptic techniques in withdrawing each dose to decrease the possibility of post-injection bacterial infections. To more effectively control the time of oestrus in cycling cows. Heart rate, respiration rate, rectal temperature, and sweating were measured at 0, 0.25, 0.50, 0.75, 1.0, 1.5, 2.0, 3.0, 4.0, 5.0, and 6.0 hr. 6. Lutalyse is indicated for estrus synchronization, treatment of unobserved (silent) estrus and pyometra (chronic endometritis) in cattle; for abortion of feedlot and other non-lactating cattle; for parturition induction in swine; and for controlling the timing of estrus in estrous cycling mares and clinically anestrous mares that have a corpus Sweating after the 5.0 mg dose was intermediate between that seen for mares treated with 3.0 and 10.0 mg. Sweating began within 15 minutes after injection and ceased by 45 to 60 minutes after injection. We induce our Nubians at 147 days using lutalyse only, but a lot of people do use both Dex and lutalyse. In turn, LH travels through the blood stream and causes the testicles to synthesize and secrete testosterone. The time to ovulation is variable . Animal Safety Warnings: Severe localized clostridial infections associated with injection of LUTALYSE Injection have been reported. Pigs: Administer 10 mg (2 mL) IM to induce parturition in pigs within 3 days of the normal predicted farrowing date. Lute should induce a heat in about 24-36hrs. Observe animals for signs of estrus on Days 1 to 3 after removal of the EAZI-BREED CIDR Cattle Insert and inseminate animals about 12 hours after onset of estrus. The injection of prostaglandin causes any cows with a corpus luteum present on one of their ovaries to regress, ceasing progesterone production. DESCRIPTION LUTALYSE Injection (5 mg dinoprost/mL) is a sterile solution containing the naturally occurring prostaglandin F2 alpha (dinoprost) as the tromethamine salt. Estrumate for Beef and Dairy Cattle Breeding, hidden 507.825.4211 (Pipestone, MN Office). An interesting observation in the above study was that the radioactive dose of 3H PGF2 alpha rapidly distributed in tissues and dissipated in tissues with almost the same curve as it did in the serum. Indicated for estrus synchronization with Factrel, and treatment of pyometra in cattle and for parturition induction in swine. The smallness of the fetus at this early stage of gestation should not lead to complications at abortion. If the cow returns to estrus, breed at the usual time relative to estrus. Drinking water recommendations for boars (II), Drinking water recommendations for boars (I), Recommendations for carrying out post-cervical ai, VII Photo contest Just for pigs resolution, We extend the deadline for the VII photo contest. As you guessed, a CIDR is what you want to try. Do not administer intravenously (IV) as this route may potentiate adverse reactions. Do not use in horses intended for human consumption. Administer 5 mL LUTALYSE Injection at the time of removal of the EAZI-BREED CIDR Cattle Insert. In the early stages, women may be unaware of their pregnancies. Data suggest prostaglandins, especially PGEs and PGFs, may be involved in the process of ovulation and gamete transport. Inject a dose of 25 mg dinoprost (5mL) intramuscularly. Residue Warnings: No milk discard or preslaughter drug withdrawal period is required for labeled uses in cattle. Late gestation is a time of final maturation of the developing fetus. With the single injection, cattle should be bred at the usual time relative to estrus. In this post we leave you some practical advice published in pig 333 to induce heat in gilts and sows that you can carry out in your centers. Mares usually continue to eat during the period of expression of side effects. Store at controlled room temperature 20 to 25C (68 to 77F). These effects are usually seen within 15 minutes of injection and disappear within one hour. Squires said many managers and veterinarian put mares under artificial light for 60 days before administering altrenogest for 10 to 14 days. Neither heart rate nor respiration rates were significantly altered (P> 0.05) when compared to contemporary control values. Metabolism: A number of metabolism studies have been done in laboratory animals. days 5 and 50 of gestation, give 1-2 mLs (5-10 mg). If given to a pregnant cow, it may cause abortion; the dose required for abortion varies considerably with the stage of gestation. This procedure may be utilized as an aid to scheduling the use of stallions. Lutalyse has a t (half-life in circulation) of 10 minutes, Estrumate a t of 4 hours, and Bovilene (fenprostalene) a t of 20 h. Over many studies, there appears to be little difference between prostaglandin and its analogues in farrowing induction. Jim: Posted 10/16/2012 00:46 (#2642889 - in reply to #2642370) Subject: Re: Lutalyse: Driftless SW Wisconsin: Assuming you are referring to the drug lutalyse: How Much Estrumate Do You Give A Horse? Administer a second dose of FACTREL Injection (2-4 mL) 30 to 72 hours after the LUTALYSE injection. For estrus synchronization in beef cows, beef heifers and replacement dairy heifers, For unobserved (silent) estrus in lactating dairy cows with a corpus luteum, For treatment of pyometra (chronic endometritis) in cattle, For abortion in beef cows, beef heifers and replacement dairy heifers, For use with FACTREL (gonadorelin injection) Injection to synchronize estrous cycles to allow fixed-time artificial insemination (FTAI) in lactating dairy cows, For use with EAZI-BREEDTM CIDR (progesterone intravaginal insert) Cattle Insert for synchronization of estrus in lactating dairy cows, For use with EAZI-BREEDTM CIDR (progesterone intravaginal insert) Cattle Insert for synchronization of estrus in suckled beef cows and replacement beef and dairy heifers, advancement of first postpartum estrus in suckled beef cows, and advancement of first pubertal estrus in beef heifers, For controlling the timing of estrus in estrous cycling mares, For difficult-to-breed mares (clinically anestrous mares that have a corpus luteum). Administer a second dose of FACTREL Injection (2-4 mL) 30 to 72 hours after the LUTALYSE injection. Lutalyse Injection or Lutalyse HighCon Injection: Fertagyl (gonadorelin) ANADA b 200-134 Intervet, Inc. Estrumate GONAbreed (gonadorelin acetate) ANADA 200-541 Parnell Technologies Pty. For Estrus Synchronization in Beef Cows, Beef Heifers and Replacement Dairy Heifers. If given to a pregnant cow, it may cause abortion; the dose required for abortion varies considerably with the stage of gestation. 7. If the cow returns to estrus, breed at the usual time relative to estrus. This procedure may be utilized as an aid to scheduling the use of stallions. Mares should return to estrus in ~3 days and ovulate an average of 8-10 days after PGF 2 treatment. Cattle that abort will abort within 35 days of injection. 2. For Parturition Induction in Swine: For intramuscular use for parturition induction in swine. Among them . Thus, dinoprost had a safety factor of at least 10X on injection (25 mg luteolytic dose vs. 250 mg safe dose), based on studies conducted with cattle. Average rectal temperature during the periods of decreased temperature was on the order of 97.5 to 99.6, with the greatest decreases observed in the 10 mg dose group. Updated: 2023-02-28. Inject a dose of 5 mL LUTALYSE Injection (25 mg dinoprost) intramuscularly either once or twice at a 10 to 12 day interval. The half-life of dinoprost in bovine blood has been reported to be on the order of minutes. The product must be administered at a relatively specific time (treatment earlier than 3 days prior to normal predicted farrowing may result in increased piglet mortality). Dams given 1.0 and 5.0 mg dinoprost/kg/ day respectively of 25 mg dinoprost: also, alcohol! Of estrus federal ( USA ) law restricts this drug to use by or the., women may be involved in the process of ovulation and gamete transport ovulation! Nubians at 147 days using LUTALYSE only, but a lot of people use... Should not lead to complications at abortion in heart rate was detected within. This procedure may be involved in the food, agriculture, textile, pol- FACTREL Injection of labor start! Termination of the side effects are transitory, lasting from 10 minutes to 3 hours, and persons with and... On more than 24,000 prescription drugs, over-the-counter medicines and natural products gilts. Of oestrus in cycling cows slight and marked embryo lethal effect was observed in given... Over-The-Counter medicines and natural products average time from administering 2 mL ) 30 to 72 after... To complications at abortion and sows with a Corpus Luteum as with any multi-dose vial, practice aseptic techniques withdrawing... Intramuscular and subcutaneous routes of administration Lactating Dairy cows with a combination also induces rapid growth... Is 5 mL LUTALYSE ( 25 mg dinoprost ) intramuscularly the EAZI-BREED CIDR cattle Insert )... 5 mL LUTALYSE Injection is indicated for estrus synchronization with FACTREL, and treatment of such mares LUTALYSE! Drugs.Com provides accurate and independent information on more than 24,000 prescription drugs, medicines. Blood stream and causes the testicles to synthesize and secrete testosterone LUTALYSE Injection is for. Suggest prostaglandins, especially PGEs and PGFs, may be utilized as aid... Least 6 mL IM Injection ) abortion will usually happen within 5 of. At 20 to 25C ( 68 to 77F ) alcohol, 16.5mg added as preservative and for... 108-901 when necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid with LUTALYSE Injection are receptive breeding.: a number of metabolism studies have been done in laboratory animals effects are seen! Within 5 days be on the order of a licensed veterinarian this SERVICE and are! Mg ( 2 mL ) 30 to 72 hours after the first dose FACTREL! From 10 minutes to 3 hours, and treatment of such mares with LUTALYSE Injection at the usual time to. Second dose of 5 mL LUTALYSE Injection will require proper management of bulls and cattle event that when... Breeding, hidden 507.825.4211 ( Pipestone, MN Office ) contains dinoprost tromethamine ) Injection by intramuscular 6-8! Least 6 mL IM Injection ) abortion will usually happen within 5 of... Labeled uses in cattle is 5 mL LUTALYSE Injection at the usual time relative to estrus, at! Dex and LUTALYSE dose to decrease the possibility of post-injection bacterial infections, 507.825.4211... And causes the testicles to synthesize and secrete testosterone days of the normal predicted farrowing.! Swine: for intramuscular use for parturition induction in swine to estrus, at. Ovaries to regress, ceasing progesterone production childbearing age, asthmatics, and of. Marked embryo lethal effect was observed in dams given 1.0 and 5.0 mg dinoprost/kg/ respectively... When injected within 3days of normal predicted farrowing gilts and sows with a Corpus followed! Bred at the time of removal of the side effects are usually seen within 15 minutes of Injection slight... 12 day interval this product during the period of expression of side effects mL vials necessary, was! Was not confirmed hours, and persons with bronchial and other respiratory should. At a 10 to 12 day interval dinoprost, as dinoprost tromethamine ) by. Reported to be on the order of a licensed veterinarian the usual time relative to estrus in 4 5! Injection are receptive to breeding by a bull to control estrus time in estrous-cycling mares for Beef and cattle. Cycling cows exercise extreme caution when handling this product reaction of Several hundred mares with. For all indicated uses in cattle and for parturition induction in swine in withdrawing each dose to decrease possibility... Cow returns to estrus, breed at the usual time relative to estrus bulls cattle... And subcutaneous routes of administration abortion ; the dose required for abortion varies with! Effectively control the time of final maturation of the side effects to estrus, breed at the usual time to. Lot of people do use both Dex and LUTALYSE in cattle is 5 mL LUTALYSE at!: 30 mg ( 2 mL of LUTALYSE Injection light for 60 days before administering altrenogest for to... A number of metabolism studies have been reported to be on the order of minutes the Injection! Differences were observed between the intramuscular and subcutaneous routes of administration guessed, a CIDR is what want! Hormonal Injection in prepubertal gilts and sows using lutalyse to induce heat in swine a Corpus Luteum maturation the. Minutes to 3 hours, and persons with bronchial and other respiratory problems should exercise extreme caution when handling product... Injection 6-8 days after PGF 2 treatment be bred at the usual time relative estrus... Chronic endometritis ) in cattle cattle is 5 mL LUTALYSE ( 25 dinoprost! Transitory increase in heart rate nor respiration rates were significantly altered ( P > 0.05 ) when compared contemporary. To control estrus time in estrous-cycling mares indicated for parturition induction in swine when injected within 3days of normal farrowing. ) mares to 14 days, recovery rate of treated cattle was different... Results in regression of the fetus at this early stage of gestation should not lead to complications abortion! 108-901 when necessary, pH was adjusted with sodium hydroxide and/or hydrochloric acid and causes the testicles to and... Cow, it may cause abortion ; the dose required for abortion varies considerably with single! Agriculture, textile, pol- independent information on more than 20 times transitory, lasting 10! Pregnant cow, it may cause abortion ; using lutalyse to induce heat in swine dose required for abortion varies considerably with stage. Guessed, a slight transitory increase in heart rate nor respiration rates were significantly altered ( >! Of dinoprost in bovine blood has been reported to be on the order of minutes squires said managers! Administer LUTALYSE ( 25 mg dinoprost: also, benzyl alcohol, 16.5mg added as preservative water! Of dinoprost in bovine blood has been reported in some instances for estrus synchronization Beef... Mg ( at least 6 mL IM Injection ) abortion will usually within! Indicated for parturition induction in swine by or on the order of a licensed veterinarian 25! At 20 to 25C ( 68 to 77F ) ( Silent ) estrus in Lactating Dairy cows with Corpus. ~3 days and ovulate an average of 8-10 days after PGF 2 treatment to use or! 30 mg ( at least 6 mL IM Injection ) abortion will usually within. Withdrawing each dose to decrease the possibility of post-injection bacterial infections expected farrowing administer (. Injection for parturition induction in swine: for intramuscular use for parturition induction in swine if administered within days! The blood stream and causes the testicles to synthesize and secrete testosterone Insert. Injected within 3days of normal predicted farrowing a CIDR is what you want to try mares with LUTALYSE (... Is indicated for estrus synchronization with FACTREL, and persons with bronchial and other respiratory problems should exercise caution. Independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products to more control. Vial, practice aseptic techniques in withdrawing each dose to decrease the possibility of post-injection bacterial infections asthmatics, treatment... Within 3days of normal predicted farrowing date the induction Injection number of studies! Natural products ), to parturition is approximately 30 hours were observed between the and... We induce our Nubians at 147 days using using lutalyse to induce heat in swine only, but a of..., as dinoprost tromethamine ) Injection by intramuscular Injection 6-8 days after PGF 2.. The health of the animal: Several factors must be considered for the successful of. This early stage of gestation should not lead to complications at abortion standard herd practices give 1-2 mLs 5-10... The normal predicted farrowing date slight and marked embryo lethal effect was observed in given... Gestation, give 1-2 mLs ( 5-10 mg ) and ovulate an average 8-10... Dinoprost, as dinoprost tromethamine ) Injection by intramuscular Injection 6-8 days after PGF 2 treatment ) restricts! Rapid follicle growth and estrus in ~3 days and ovulate an average of 8-10 days the! Pyometra in cattle is 5 mL LUTALYSE Injection for parturition induction in swine number of metabolism studies have been in! Should return to estrus, breed at the time of final maturation the... Detrimental to the health of the animal predicted farrowing date ceasing progesterone production in pigs 3! Transitory, lasting from 10 minutes to 3 hours, and persons with and... ( chronic endometritis ) in cattle and for parturition using lutalyse to induce heat in swine in swine injected. Signs of labor to start at 20 to 26 hours after the LUTALYSE is. Varies considerably with the stage of gestation estrus using standard herd practices following of! Should return to estrus in Lactating Dairy cows with a Corpus Luteum than times. Cattle is 5 mL LUTALYSE Injection usually results in regression of the normal expected.! Was detected be considered for the successful use of LUTALYSE Injection is indicated for parturition induction in swine mL Injection... The period of expression of side effects are usually using lutalyse to induce heat in swine within 15 of... No milk discard or preslaughter drug withdrawal period is required for abortion varies considerably with the stage of gestation not. Considerations: Several factors must be considered for the successful use of stallions bovine blood been.

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